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MD Pharmacology NMC syllabus ~5 min read Recent advances last updated on 2026-09-08

Chronopharmacology & Chronotherapeutics

Biological Clocks, Drug Exposure and Evidence for Timed Therapy

Past RGUHS + DNB + MPMSU + MUHS + VNSGU + WBUHS · 22 RGUHSMar '26 RGUHSSep '25 MPMSUJan '25 RGUHSDec '23 RGUHSJul '23 MPMSU2022 WBUHSMay '22 MUHSWinter '22 RGUHSJun '20 MPMSUJul '20 DNBJun '20 MUHSSummer '19 MUHSSummer '18 VNSGUMay '17 MUHSSummer '17 Suppl VNSGUApr '16 DNBDec '16 WBUHS2016 RGUHSOct '10 WBUHSApr '08 RGUHSApr '07 RGUHSApr '06

Definition and aims

  • Chronopharmacology — studies relationships between drug effects and circadian rhythms; biological time supplements drug, dose and route.
  • Chronotherapeutics — arranges administration or exposure around a relevant biological rhythm to improve treatment.
  • Three purposes — approximate hormone secretion, inhibit greater target activity, or anticipate symptoms; timing must suit the drug, formulation and patient.
Figure 1 — Daily rhythms and disease: typical patterns
Figure 1 — Daily rhythms and disease: typical patterns
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Chronopharmacology Chronotherapeutics

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