Antimalarial Drugs
Resistant & Cerebral Malaria — Classification, ACT, Resistance Mechanisms & Emergency Management
Past RGUHS + DNB + MPMSU + MUHS + VNSGU · 59
RGUHSMar '26
MPMSUMay '25
MPMSUJan '25
MPMSUJan '25
VNSGUSep '25
DNBMay '24
DNBOct '24
MPMSUJun '23
MPMSUJun '23
MUHSSummer '23
MUHSWinter '23
RGUHSNov '22
MPMSU2022
MUHSWinter '22
RGUHSNov '21
RGUHSJul '21
DNBJun '21
MUHSSummer '21
VNSGUJun '21
MPMSUJul '20
DNBJun '20
DNBJun '20
MPMSU2019
MUHSWinter '19
RGUHSNov '18
RGUHSMay '18
MPMSUMay '18
RGUHSNov '17
MPMSU2017
MPMSU2017
MUHSSummer '17
MUHSSummer '17 Suppl
RGUHSNov '16
RGUHSJun '16
DNBDec '16
DNBDec '16
MPMSU2015
MPMSU2015
MUHSSummer '15
MUHSWinter '15
DNBDec '14
DNBDec '12
MPMSU2011
RGUHSOct '10
MPMSU2010
RGUHSOct '09
MPMSU2009
MPMSU2008
MPMSU2007
RGUHSApr '06
MPMSU2005
MPMSU2004
MPMSU2002
MPMSU1999
MPMSU1998
MPMSU1998
MPMSU1997
MPMSU1995
MPMSU1993
Introduction
- Antimalarials are drugs used for the prophylaxis, treatment, and prevention of relapse of malaria, acting on one or more stages of the Plasmodium life cycle in the human host.
- Malaria is caused by protozoa of the genus Plasmodium; five species infect humans — P. falciparum, P. vivax, P. ovale, P. malariae, P. knowlesi. P. falciparum causes most severe disease and deaths; P. vivax dominates in South Asia and is increasingly a cause of severe malaria.
- Global burden ~a quarter-billion cases and >600,000 deaths/year; malaria remains a top-five killer of children <5 yr. Two clinical problems dominate the modern exam: drug-resistant (chloroquine-resistant, multidrug-resistant) P. falciparum and cerebral malaria.
- India / NCVBDC context: CQ-resistant P. falciparum is now widespread (no fully sensitive area), so national policy is ACT for all P. falciparum plus single-dose gametocidal primaquine; the falling case trend is attributed to effective ACT use.
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Antimalarial Drugs
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